Title : Targeting chronic NFAT activation with calcineurin inhibitors in diffuse large B-cell lymphoma.

Pub. Date : 2020 Jan 9

PMID : 31794606






1 Functional Relationships(s)
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1 Intriguingly, although NFAT is activated in both DLBCL subtypes, long-term calcineurin inhibition with cyclosporin A or FK506, both clinically approved drugs, triggers potent cytotoxicity specifically in ABC DLBCL cells. Tacrolimus ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens