Pub. Date : 2019
PMID : 31787922
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | While the pathogenesis of both diseases is different, disruption of intracellular cholesterol trafficking has emerged as a common feature of both AD and NPC disease. | Cholesterol | NPC intracellular cholesterol transporter 1 | Homo sapiens |
| 2 | In addition to the primary accumulation of cholesterol and sphingolipids in lysosomes, NPC disease is also characterized by an increase in mitochondrial cholesterol levels in affected organs, predominantly in brain and liver. | Cholesterol | NPC intracellular cholesterol transporter 1 | Homo sapiens |
| 3 | In addition to the primary accumulation of cholesterol and sphingolipids in lysosomes, NPC disease is also characterized by an increase in mitochondrial cholesterol levels in affected organs, predominantly in brain and liver. | Cholesterol | NPC intracellular cholesterol transporter 1 | Homo sapiens |