Pub. Date : 2020 Jan
PMID : 31786978
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | This has led to development of RB150, an orally active prodrug of the specific and selective APA inhibitor, EC33. | firibastat | glutamyl aminopeptidase | Rattus norvegicus |
| 2 | Orally administered RB150 crosses the gastrointestinal and blood-brain barriers, enters the brain where it generates 2 active molecules of EC33 that block brain APA activity. | firibastat | glutamyl aminopeptidase | Rattus norvegicus |