Title : GPX2 silencing relieves epithelial-mesenchymal transition, invasion, and metastasis in pancreatic cancer by downregulating Wnt pathway.

Pub. Date : 2020 Nov

PMID : 31774184






2 Functional Relationships(s)
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1 The regulatory function of GPX2 in PC was explored by treatment with short hairpin RNA against GPX2 or LiCl (activator of wingless-type MMTV integration site [Wnt] pathway) in PC cells. Lithium Chloride glutathione peroxidase 2 Homo sapiens
2 Furthermore, the trend of EMT and invasion and metastasis of PC induced by the LiCl-activated Wnt pathway was reversed when the GPX2 was silenced. Lithium Chloride glutathione peroxidase 2 Homo sapiens