Title : Linker Editing of Pneumococcal Lysin ClyJ Conveys Improved Bactericidal Activity.

Pub. Date : 2020 Jan 27

PMID : 31767724






1 Functional Relationships(s)
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1 Our previous work reported a pneumococcal-specific chimeric lysin, ClyJ, which combines the CHAP (cysteine, histidine-dependent amidohydrolase/peptidase) enzymatically active domain (EAD) from the PlyC lysin and the cell-wall binding domain (CBD) from the phage SPSL1 lysin, which imparts choline binding specificity. histidine-pyridine-histidine-3 synaptopodin 2-like Mus musculus