Title : Formation of 5α-dihydrotestosterone from 5α-androstane-3α,17β-diol in prostate cancer LAPC-4 cells - Identifying inhibitors of non-classical pathways producing the most potent androgen.

Pub. Date : 2020 Jan 15

PMID : 31753699






1 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 The most potent inhibitor 25 (IC50 = 1.2 muM) possesses a 4-(4-CF3-3-CH3O-benzyl)piperazinyl methyl side chain at C3beta and 17beta-OH/17alpha-CCH functionalities at C17 of a 5alpha-androstane core. androstane endogenous retrovirus group K member 3 Homo sapiens