Title : Germline polymorphisms associated with impaired survival outcomes and somatic tumor alterations in advanced prostate cancer.

Pub. Date : 2020 Jun

PMID : 31745256






1 Functional Relationships(s)
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1 CONCLUSIONS: This study presents a comprehensive assessment of germline variants in androgen metabolism genes and highlights HSD3B1 polymorphisms as prognostic of OS after ADT and associated with an aggressive gene expression tumor profile in mCRPC. adt hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 Homo sapiens