Pub. Date : 2019
PMID : 31741857
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | AIM: To study the inhibition effect of TAK-242 on the proliferation of rat eye Tenon"s capsule fibroblasts via the toll-like receptor 4 (TLR4) signaling pathway. | ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate | toll-like receptor 4 | Rattus norvegicus |
| 2 | AIM: To study the inhibition effect of TAK-242 on the proliferation of rat eye Tenon"s capsule fibroblasts via the toll-like receptor 4 (TLR4) signaling pathway. | ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate | toll-like receptor 4 | Rattus norvegicus |
| 3 | CONCLUSION: TAK-242 inhibits the proliferation of LPS-induced Tenon"s capsule fibroblasts and the release of inflammatory factors by regulating the TLR4 signaling pathway, providing a new idea for reducing the scarring of the filter passage after glaucoma filtration surgery. | ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate | toll-like receptor 4 | Rattus norvegicus |