Pub. Date : 2019 Nov 15
PMID : 31731717
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Additionally, after combined therapy with simvastatin and lunasin for four weeks, ApoE-/- mice had significantly lower PCSK9 and higher LDLR levels in hepatic tissues and remarkably reduced plasma concentrations of total cholesterol (TC) and LDL-C, as compared to each monotherapy. | LUNASINE | proprotein convertase subtilisin/kexin type 9 | Mus musculus |
| 2 | Conclusively, lunasin significantly improved the LDL-C lowering efficacy of simvastatin by counteracting simvastatin induced elevation of PCSK9 in hepatocytes and ApoE-/- mice. | LUNASINE | proprotein convertase subtilisin/kexin type 9 | Mus musculus |