Title : Cell-Free NADPH Oxidase Activation Assays: A Triumph of Reductionism.

Pub. Date : 2020

PMID : 31729001






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The superoxide (O2 -)-generating NADPH oxidase complex of phagocytes comprises a membrane-associated heterodimeric flavocytochrome, known as cytochrome b 558 (consisting of NOX2 and p22phox) and four cytosolic regulatory proteins, p47phox, p67phox, p40phox, and the small GTPase Rac. NADP mitochondrially encoded cytochrome b Homo sapiens
2 Thus, a mixture of the individual components of the NADPH oxidase is exposed in vitro to an activating agent, the most common being anionic amphiphiles, resulting in the formation of a complex between cytochrome b 558 and the cytosolic components and O2 - generation in the presence of NADPH. NADP mitochondrially encoded cytochrome b Homo sapiens
3 Thus, a mixture of the individual components of the NADPH oxidase is exposed in vitro to an activating agent, the most common being anionic amphiphiles, resulting in the formation of a complex between cytochrome b 558 and the cytosolic components and O2 - generation in the presence of NADPH. NADP mitochondrially encoded cytochrome b Homo sapiens