Title : Identification of A Novel Class of Benzofuran Oxoacetic Acid-Derived Ligands that Selectively Activate Cellular EPAC1.

Pub. Date : 2019 Nov 12

PMID : 31726720






1 Functional Relationships(s)
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1 We next generated a limited library of 91 analogues of SY000 and identified SY009, with modifications to the benzofuran ring associated with a 10-fold increase in potency towards EPAC1 over SY000 in binding assays. benzofuran Rap guanine nucleotide exchange factor 3 Homo sapiens