Title : 25-HC promotes hepatocellular carcinoma metastasis through up-regulation of TLR4 dependent FABP4.

Pub. Date : 2019

PMID : 31720079






3 Functional Relationships(s)
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1 Mechanistically, the promotive effect of 25-HC was through up-regulation of Toll-like receptor 4 (TLR4) dependent fatty acid binding protein 4 (FABP4). 25-hydroxycholesterol toll like receptor 4 Homo sapiens
2 Mechanistically, the promotive effect of 25-HC was through up-regulation of Toll-like receptor 4 (TLR4) dependent fatty acid binding protein 4 (FABP4). 25-hydroxycholesterol toll like receptor 4 Homo sapiens
3 In summary, our study reveals the effects and mechanism of 25-HC/TLR4/FABP4 axis in promoting HCC metastasis, which provides novel avenue for therapeutic intervention against HCC progression. 25-hydroxycholesterol toll like receptor 4 Homo sapiens