Pub. Date : 2020 Feb
PMID : 31698019
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Gastrodin protects against glutamate-induced ferroptosis in HT-22 cells through Nrf2/HO-1 signaling pathway. | gastrodin | nuclear factor, erythroid derived 2, like 2 | Mus musculus |
| 2 | Results showed that GAS inhibited glutamate-induced ferroptosis via Nrf2/HO-1 signaling pathway. | gastrodin | nuclear factor, erythroid derived 2, like 2 | Mus musculus |
| 3 | We found that GAS increased the nuclear translocation of Nrf2, up-regulated the downstream HO-1 protein expression in HT-22 cells following treatment with glutamate. | gastrodin | nuclear factor, erythroid derived 2, like 2 | Mus musculus |
| 4 | In conclusion, these results show that GAS protects HT-22 cells from the ferroptosis induced by glutamate through a new mechanism of Nrf2/HO-1 signaling pathway. | gastrodin | nuclear factor, erythroid derived 2, like 2 | Mus musculus |