Pub. Date : 2019 Dec
PMID : 31693935
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | miR-145-5p overexpression repressed CRC cell proliferation, invasion, migration and induced apoptosis, and these effects were reversed by RHBDD1 upregulation. | mir-145-5p | rhomboid domain containing 1 | Homo sapiens |
2 | In conclusion, our study revealed that miR-145-5p overexpression inhibited tumorigenesis in CRC by downregulating RHBDD1 via suppressing the EGFR-associated signaling pathway (EGFR/Raf/MEK/ERK cascades). | mir-145-5p | rhomboid domain containing 1 | Homo sapiens |