Title : Continentalic Acid Rather Than Kaurenoic Acid Is Responsible for the Anti-Arthritic Activity of Manchurian Spikenard In Vitro and In Vivo.

Pub. Date : 2019 Nov 4

PMID : 31690022






1 Functional Relationships(s)
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1 The spikenard extract significantly inhibited IL-1beta-stimulated production of IL-6, IL-8, metalloproteinase (MMP)-1, MMP-13, cyclooxygenase (COX)-2, inducible nitric oxide synthase (iNOS) and prostaglandin(PG)E2 in a dose-dependent manner but not MMP-3 production. Prostaglandins E interleukin 1 beta Rattus norvegicus