Title : Amphiphilic Polypeptoids Rupture Vesicle Bilayers To Form Peptoid-Lipid Fragments Effective in Enhancing Hydrophobic Drug Delivery.

Pub. Date : 2019 Nov 26

PMID : 31686512






1 Functional Relationships(s)
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1 Using the kinase inhibitor, Sorafenib as a model drug, it is shown that HMP-lipid fragments containing the drug can efficiently enter a hepatocellular carcinoma cell line (Huh 7.5), indicating the use of such fragments as drug delivery nanocarriers. Sorafenib MIR7-3 host gene Homo sapiens