Title : AIB1 sequestration by androgen receptor inhibits estrogen-dependent cyclin D1 expression in breast cancer cells.

Pub. Date : 2019 Nov 4

PMID : 31684907






2 Functional Relationships(s)
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Compound Name
Protein Name
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1 These effects involve the competition between AR and ERalpha for the interaction with the steroid receptor coactivator AIB1, a limiting factor in the functional coupling of the ERalpha with the cyclin D1 promoter. Steroids estrogen receptor 1 Homo sapiens
2 Co-immunoprecipitation studies indicated that the preferential interaction of AIB1 with ERalpha or AR depends on the intracellular expression levels of the two steroid receptors. Steroids estrogen receptor 1 Homo sapiens