Title : Protective effects of trimetazidine and coenzyme Q10 on cisplatin-induced cardiotoxicity by alleviating oxidative stress and mitochondrial dysfunction.

Pub. Date : 2019 Nov

PMID : 31674935






1 Functional Relationships(s)
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1 The combined use of TMZ and CoQ10 treatment was more effective than using either agent alone (p<0.01 for ROS, MDA, CAT, and cytosolic cyto-c; p<0.05 for SOD, nuclear Nrf2, and DeltaPsim loss). Trimetazidine catalase Rattus norvegicus