Title : SDR9C7 catalyzes critical dehydrogenation of acylceramides for skin barrier formation.

Pub. Date : 2020 Feb 3

PMID : 31671075






1 Functional Relationships(s)
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1 In a patient with SDR9C7 mutation and a mouse Sdr9c7-KO model, we show loss of covalent binding of epidermal ceramides to protein, a structural fault in the barrier. Ceramides 4short chain dehydrogenase/reductase family 9C, member 7 Mus musculus