Title : Human tissue factor contains thioester-linked palmitate and stearate on the cytoplasmic half-cystine.

Pub. Date : 1988 Jun 14

PMID : 3166978






7 Functional Relationships(s)
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1 The results indicate that the four half-cystines in the extracellular domain of TF form two disulfide bonds and the half-cystine in the cytoplasmic region is acylated by palmitic acid and stearic acid. Disulfides coagulation factor III, tissue factor Homo sapiens
2 Deacylation of TF with hydroxylamine resulted in the spontaneous generation of disulfide-linked TF dimers. Disulfides coagulation factor III, tissue factor Homo sapiens
3 Deacylation of TF with hydroxylamine resulted in the spontaneous generation of disulfide-linked TF dimers. Disulfides coagulation factor III, tissue factor Homo sapiens
4 This result suggests that the disulfide-linked TF dimer, a minor component of most TF preparations, and the recently described heterodimeric form of TF are artifacts produced by deacylation of Cys245 and subsequent interchain disulfide bond formation. Disulfides coagulation factor III, tissue factor Homo sapiens
5 This result suggests that the disulfide-linked TF dimer, a minor component of most TF preparations, and the recently described heterodimeric form of TF are artifacts produced by deacylation of Cys245 and subsequent interchain disulfide bond formation. Disulfides coagulation factor III, tissue factor Homo sapiens
6 This result suggests that the disulfide-linked TF dimer, a minor component of most TF preparations, and the recently described heterodimeric form of TF are artifacts produced by deacylation of Cys245 and subsequent interchain disulfide bond formation. Disulfides coagulation factor III, tissue factor Homo sapiens
7 This result suggests that the disulfide-linked TF dimer, a minor component of most TF preparations, and the recently described heterodimeric form of TF are artifacts produced by deacylation of Cys245 and subsequent interchain disulfide bond formation. Disulfides coagulation factor III, tissue factor Homo sapiens