Title : Epigenetic silencing of SALL2 confers tamoxifen resistance in breast cancer.

Pub. Date : 2019 Dec

PMID : 31657150






1 Functional Relationships(s)
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1 By contrast, silencing SALL2 induced downregulation of ERalpha and PTEN and activated the Akt/mTOR signaling, resulting in estrogen-independent growth and tamoxifen resistance in ERalpha-positive breast cancer. Tamoxifen AKT serine/threonine kinase 1 Homo sapiens