Title : Adenylyl Cyclase Type 8 Overexpression Impairs Phosphorylation-Dependent Orai1 Inactivation and Promotes Migration in MDA-MB-231 Breast Cancer Cells.

Pub. Date : 2019 Oct 23

PMID : 31652779






3 Functional Relationships(s)
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1 In MDA-MB-231 cells, we found that AC8 overexpression reduces the Orai1 phosphoserine content, thus suggesting that AC8 interferes with Orai1 serine phosphorylation, which takes place at residues located in the AC8-binding site. cholecystokinin C-terminal flanking peptide adenylate cyclase 8 Homo sapiens
2 In MDA-MB-231 cells, we found that AC8 overexpression reduces the Orai1 phosphoserine content, thus suggesting that AC8 interferes with Orai1 serine phosphorylation, which takes place at residues located in the AC8-binding site. cholecystokinin C-terminal flanking peptide adenylate cyclase 8 Homo sapiens
3 In MDA-MB-231 cells, we found that AC8 overexpression reduces the Orai1 phosphoserine content, thus suggesting that AC8 interferes with Orai1 serine phosphorylation, which takes place at residues located in the AC8-binding site. cholecystokinin C-terminal flanking peptide adenylate cyclase 8 Homo sapiens