Title : Involvement of Estrogen Receptor-α in the Activation of Nrf2-Antioxidative Signaling Pathways by Silibinin in Pancreatic β-Cells.

Pub. Date : 2020 Mar 1

PMID : 31649209






1 Functional Relationships(s)
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1 Accordingly, silibinin (10 muM) elevated viability, insulin biosynthesis, and insulin secretion of high glucose/palmitate-treated INS-1 cells accompanied by increased expression of ERalpha, Nrf2, and HO-1 as well as decreased reactive oxygen species production in vitro. Glucose insulin 1 Rattus norvegicus