Pub. Date : 2019 Oct 23
PMID : 31647033
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | AURKA inhibition using 100 nM MLN8237 for 48 h decreases cell growth in a partially P53-dependent manner, and the survival rates of H460, HCC2429, and H1299 cells were 56, 50, and 77%, respectively. | MLN 8237 | tumor protein p53 | Homo sapiens |
| 2 | Modulation of P53 function could provide a new option for reversing cell resistance to the AURKA inhibitor MLN8237, which deserves further investigation. | MLN 8237 | tumor protein p53 | Homo sapiens |