Title : Target of MCC950 in Inhibition of NLRP3 Inflammasome Activation: a Literature Review.

Pub. Date : 2020 Feb

PMID : 31646445






1 Functional Relationships(s)
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1 Accumulating investigations imply that chloride efflux-dependent ASC speck oligomerization and potassium efflux-dependent activation of caspase-1 are the two relatively independent, but indispensable events for NLRP3 inflammasome activation. Chlorides NLR family pyrin domain containing 3 Homo sapiens