Title : IL-17 stimulates the expression of CCL2 in cardiac myocytes via Act1/TRAF6/p38MAPK-dependent AP-1 activation.

Pub. Date : 2020 Jan

PMID : 31630418






1 Functional Relationships(s)
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1 After blocking Act1/TRAF6/p38MAPK cascade and interfering AP-1 with Curcumin or c-Jun siRNA, CCL2 expression induced by IL-17 was significantly attenuated at both mRNA and protein levels. Curcumin C-C motif chemokine ligand 2 Homo sapiens