Pub. Date : 2019 Dec
PMID : 31629252
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Ginsenoside Rg3 regulates DNA damage in non-small cell lung cancer cells by activating VRK1/P53BP1 pathway. | ginsenoside Rg3 | vaccinia related kinase 1 | Mus musculus |
| 2 | Ginsenoside Rg3 increased the mRNA and protein expression of VRK1 in NSCLC cells as measured by RT-qPCR and western blot, respectively. | ginsenoside Rg3 | vaccinia related kinase 1 | Mus musculus |
| 3 | These findings suggests that ginsenoside Rg3 regulates VRK1 signaling. | ginsenoside Rg3 | vaccinia related kinase 1 | Mus musculus |
| 4 | Taken together, these results show that ginsenoside Rg3 upregulate VRK1 expression and P53BP1 foci formation in response to DNA damage thereby inhibiting the tumorigenesis and viability of cancer cells. | ginsenoside Rg3 | vaccinia related kinase 1 | Mus musculus |