Pub. Date : 2020 May
PMID : 31628683
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The blockage of AQP2, or its physically-associated calcium channel TRPV4, significantly reduced lamellipodia NHE1 activity. | Calcium | transient receptor potential cation channel subfamily V member 4 | Homo sapiens |
| 2 | Our data suggest that AQP2 modulates the activity of NHE1 through its calcium channel partner TRPV4, thereby determining pH-dependent actin polymerization, providing mechanical stability to delineate lamellipodia structure and defining the efficiency of cell migration. | Calcium | transient receptor potential cation channel subfamily V member 4 | Homo sapiens |