Title : The 11β-hydroxyandrostenedione pathway and C11-oxy C21 backdoor pathway are active in benign prostatic hyperplasia yielding 11keto-testosterone and 11keto-progesterone.

Pub. Date : 2020 Feb

PMID : 31626910






1 Functional Relationships(s)
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1 However, the adrenal C11-oxy C19 steroid, 11beta-hydroxyandrostenedione (11OHA4), also contributes to the active androgen pool in the prostate microenvironment, and while it has been shown to impact castration resistant prostate cancer, the C11-oxy C19 steroids together with the C11-oxy C21 steroids have not been studied in BPH. Steroids TBL1X/Y related 1 Homo sapiens