Title : The redox-active site of thioredoxin is directly involved in apoptosis signal-regulating kinase 1 binding that is modulated by oxidative stress.

Pub. Date : 2020 Apr

PMID : 31623019






1 Functional Relationships(s)
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1 Although oxidative stress induces relatively moderate structural changes in thioredoxin, the formation of intramolecular disulfide bridges leads to a considerable conformational rearrangement of the thioredoxin-binding interface on ASK1. Disulfides thioredoxin Homo sapiens