Title : Inhibition of histone deacetylase 2 reduces MDM2 expression and reduces tumor growth in dedifferentiated liposarcoma.

Pub. Date : 2019 Oct 1

PMID : 31620242






1 Functional Relationships(s)
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1 In vitro, treatment of DDLPS cell lines with the HDAC inhibitors MI-192 (HDAC2/3 inhibitor) or romidepsin (HDAC1/2 inhibitor) reduced MDM2 expression and induced apoptosis. romidepsin transformed mouse 3T3 cell double minute 2 Mus musculus