Pub. Date : 2019 Dec
PMID : 31610054
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Allosteric Discrimination at the NADH/ADP Regulatory Site of Glutamate Dehydrogenase. | NAD | glutamate dehydrogenase 1 | Homo sapiens |
| 2 | Our computational investigation of the NADH/ADP site presented in this paper provides insight into the opposite allosteric effects induced at a single site of binding inhibitor NADH versus activator ADP to GDH. | NAD | glutamate dehydrogenase 1 | Homo sapiens |
| 3 | Our computational investigation of the NADH/ADP site presented in this paper provides insight into the opposite allosteric effects induced at a single site of binding inhibitor NADH versus activator ADP to GDH. | NAD | glutamate dehydrogenase 1 | Homo sapiens |
| 4 | Our simulations show an interesting model of ADP with dissimilar binding conformations at each NADH/ADP site in the GDH trimer, which explains the poorly understood strong binding but weak activation shown in experimental studies. | NAD | glutamate dehydrogenase 1 | Homo sapiens |