Title : Deoxyguanosine is a TLR7 agonist.

Pub. Date : 2020 Jan

PMID : 31608988






1 Functional Relationships(s)
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1 Here, we report that deoxyguanosine (dG) triggered cytokine production in murine bone marrow derived macrophages and plasmacytoid dendritic cells, as well as in human peripheral blood mononuclear cells, including type I interferons (IFNs) and pro-inflammatory factors such as TNF and IL-6. Deoxyguanosine tumor necrosis factor Homo sapiens