Title : Melatonin attenuates epidermal growth factor-induced cathepsin S expression in ARPE-19 cells: Implications for proliferative vitreoretinopathy.

Pub. Date : 2020 Jan

PMID : 31605630






1 Functional Relationships(s)
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1 Taken together, these data indicate that melatonin inhibited EGF-induced proliferation and motility of human ARPE-19 cells by activating the AKT/mTOR pathway, which is dependent on CTSS modulation of c-Jun/Sp1 signalling. Melatonin AKT serine/threonine kinase 1 Homo sapiens