Title : Selective inhibition of APOBEC3 enzymes by single-stranded DNAs containing 2'-deoxyzebularine.

Pub. Date : 2019 Nov 6

PMID : 31603457






2 Functional Relationships(s)
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1 Here, we use the discriminative properties of wild-type APOBEC3A, APOBEC3B and APOBEC3G to deaminate different cytosines in the CCC-recognition motif in order to best place the cytidine analogue 2"-deoxyzebularine (dZ) in the CCC-motif. 2'-deoxyzebularine apolipoprotein B mRNA editing enzyme catalytic subunit 3B Homo sapiens
2 Here, we use the discriminative properties of wild-type APOBEC3A, APOBEC3B and APOBEC3G to deaminate different cytosines in the CCC-recognition motif in order to best place the cytidine analogue 2"-deoxyzebularine (dZ) in the CCC-motif. 2'-deoxyzebularine apolipoprotein B mRNA editing enzyme catalytic subunit 3B Homo sapiens