Pub. Date : 2019 Dec
PMID : 31587572
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | During the developmental stage of Ang II-salt hypertension, L-PGDS expression was higher in cerebrospinal fluid, and PGD2 levels were increased in the choroid plexus, cerebrospinal fluid, and the cardioregulatory brain region rostral ventrolateral medulla. | Salts | angiogenin | Rattus norvegicus |
| 2 | Blockade of DP1R with BWA868C, however, increased the magnitude of Ang II-salt hypertension and significantly increased neurogenic pressor activity. | Salts | angiogenin | Rattus norvegicus |
| 3 | In summary, we establish that the development of Ang II-salt hypertension requires increased COX- and L-PGDS-derived PGD2 production in the brain, making L-PGDS a possible target for treating neurogenic hypertension. | Salts | angiogenin | Rattus norvegicus |