Title : Structure-activity relationship and in vitro inhibition of human cytochrome CYP2A6 and CYP2A13 by flavonoids.

Pub. Date : 2020 Jun

PMID : 31578905






1 Functional Relationships(s)
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1 While the liver-specific CYP2A6 is associated with the nicotine clearance and smoking addiction, the metabolic activation of the tobacco-specific nitrosamine by lung-specific CYP2A13 can lead to lung tumorigenesis. Nicotine cytochrome P450 family 2 subfamily A member 6 Homo sapiens