Title : Pimozide suppresses cancer cell migration and tumor metastasis through binding to ARPC2, a subunit of the Arp2/3 complex.

Pub. Date : 2019 Dec

PMID : 31571309






2 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Pimozide suppresses cancer cell migration and tumor metastasis through binding to ARPC2, a subunit of the Arp2/3 complex. Pimozide actin related protein 2 Homo sapiens
2 Pimozide increased the lag phase of Arp2/3 complex-dependent actin polymerization and inhibited the vinculin-mediated recruitment of ARPC2 to focal adhesions in cancer cells. Pimozide actin related protein 2 Homo sapiens