Pub. Date : 2019 Dec 1
PMID : 31563592
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Famotidine has a neuroprotective effect on MK-801 induced toxicity via the Akt/GSK-3beta/beta-catenin signaling pathway in the SH-SY5Y cell line. | Famotidine | AKT serine/threonine kinase 1 | Homo sapiens |
| 2 | In this study, we aimed to investigate the effects of famotidine on the Akt/GSK-3beta/beta-catenin signaling pathway on SH-SY5Y neuroblastoma cells in the presence of MK-801. | Famotidine | AKT serine/threonine kinase 1 | Homo sapiens |
| 3 | Overall, the present results suggest that famotidine has a neuroprotective effect against MK-801 via modulation of the Akt/GSK-3beta/beta-catenin signaling pathway, an important mechanism in schizophrenia neurobiology. | Famotidine | AKT serine/threonine kinase 1 | Homo sapiens |