Title : Heat Shock Factor 1 Is a Direct Antagonist of AMP-Activated Protein Kinase.

Pub. Date : 2019 Nov 21

PMID : 31561952






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 By physically evoking conformational switching of AMPK, HSF1 impairs AMP binding to the gamma subunits and enhances the PP2A-mediated de-phosphorylation, but it impedes the LKB1-mediated phosphorylation of Thr172, and retards ATP binding to the catalytic alpha subunits. Adenosine Monophosphate serine/threonine kinase 11 Homo sapiens