Title : Sirtuin4 suppresses the anti-neuroinflammatory activity of infiltrating regulatory T cells in the traumatically injured spinal cord.

Pub. Date : 2019 Dec

PMID : 31559637






1 Functional Relationships(s)
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1 Furthermore, SIRT4 down-regulated 5" AMP-activated protein kinase (AMPK) signaling in Treg cells, whereas the AMPK agonist AICAR restored the expression of Foxp3 and interleukin-10 in SIRT4-overexpressing Treg cells. AICA ribonucleotide protein kinase AMP-activated non-catalytic subunit beta 1 Homo sapiens