Title : A mitochondria-targeted fatty acid analogue influences hepatic glucose metabolism and reduces the plasma insulin/glucose ratio in male Wistar rats.

Pub. Date : 2019

PMID : 31550253






1 Functional Relationships(s)
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1 In addition, pyruvate dehydrogenase activity was reduced, accompanied by 10-15-fold increased gene expression of its regulator pyruvate dehydrogenase kinase 4 compared to control, suggesting reduced entry of pyruvate into the TCA cycle. Pyruvates pyruvate dehydrogenase kinase 4 Rattus norvegicus