Title : Proinflammatory profile of neonatal monocytes induced by microbial ligands is downmodulated by histamine.

Pub. Date : 2019 Sep 23

PMID : 31548589






3 Functional Relationships(s)
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1 Evaluation of the effect of histamine on LPS-induced CCL2 secretion showed an inhibitory effect in the majority of adults, whereas this effect was detectable in all NBs. Histamine C-C motif chemokine ligand 2 Homo sapiens
2 Histamine receptor (HR) blockage revealed partial involvement of H1R, H2R and H4R in LPS-induced CCL2 inhibition in MNCs from both NBs and adults. Histamine C-C motif chemokine ligand 2 Homo sapiens
3 The immunomodulatory role of histamine on CCL2 and CXCL8 was detected at the transcript and protein levels. Histamine C-C motif chemokine ligand 2 Homo sapiens