Title : Inhibition of PI3K pathway using BKM120 intensified the chemo-sensitivity of breast cancer cells to arsenic trioxide (ATO).

Pub. Date : 2019 Nov

PMID : 31539632






1 Functional Relationships(s)
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1 Our findings also showed that BKM120 augmented ATO-induced anti-proliferative effects through inducing G1 arrest and reducing the incorporation of BrdU into the synthesized DNA of drugs-treated cells, which was coupled with c-Myc-mediated suppression of hTERT expression. Arsenic Trioxide telomerase reverse transcriptase Homo sapiens