Title : MicroRNA Mediated Changes in Drug Metabolism and Target Gene Expression by Efavirenz and Rifampicin In Vitro: Clinical Implications.

Pub. Date : 2019 Oct

PMID : 31526233






1 Functional Relationships(s)
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1 On the other hand, treatment of HepaRG cells with RMP resulted in a significant increase in mRNA expression for CYP2B6 (6.68-fold, p = 0.007) and CYP3A4 (111.96-fold, p = 0.001), whereas NR1I3 expression decreased (0.46-fold, p = 0.033). Rifampin cytochrome P450 family 2 subfamily B member 6 Homo sapiens