Title : The histamine-4 receptor antagonist JNJ7777120 prevents immune abnormalities by inhibiting RORĪ³t/T-bet transcription factor signaling pathways in BTBR T+ Itpr3tf/J mice exposed to gamma rays.

Pub. Date : 2019 Oct

PMID : 31522074






1 Functional Relationships(s)
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1 Additionally, JNJ-treated and irradiation-exposed BTBR mice exhibited decreases in IL-17A-, RORgammaT-, IL-22-, T-bet-, and STAT3-producing CD8+ T cells and increases in ICOS- and Foxp3-producing CD8+ T cells. btbr interleukin 22 Mus musculus