Pub. Date : 2019 Sep 11
PMID : 31511040
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | circPTN sponges miR-145-5p/miR-330-5p to promote proliferation and stemness in glioma. | circptn | microRNA 330 | Homo sapiens |
| 2 | Furthermore, we performed dual-luciferase reporter assays and RNA pull-down assays to verify that circPTN acts through sponging miR-145-5p and miR-330-5p. | circptn | microRNA 330 | Homo sapiens |
| 3 | Increasing expression of circPTN rescued the inhibition of proliferation and downregulation of SOX9/ITGA5 in glioma cells by miR-145-5p/miR-330-5p. | circptn | microRNA 330 | Homo sapiens |
| 4 | CONCLUSIONS: Our results suggest that circPTN is an oncogenic factor that acts by sponging miR-145-5p/miR-330-5p in glioma. | circptn | microRNA 330 | Homo sapiens |