Title : LL1, a novel and highly selective STAT3 inhibitor, displays anti-colorectal cancer activities in vitro and in vivo.

Pub. Date : 2020 Jan

PMID : 31499589






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 KEY RESULTS: LL1 is highly selective among STATs family members and specifically inhibits phosphorylation of STAT3 Tyr-705 site, blocking the whole transmission process of STAT3 signaling. Tyrosine signal transducer and activator of transcription 3 Homo sapiens
2 KEY RESULTS: LL1 is highly selective among STATs family members and specifically inhibits phosphorylation of STAT3 Tyr-705 site, blocking the whole transmission process of STAT3 signaling. Tyrosine signal transducer and activator of transcription 3 Homo sapiens
3 KEY RESULTS: LL1 is highly selective among STATs family members and specifically inhibits phosphorylation of STAT3 Tyr-705 site, blocking the whole transmission process of STAT3 signaling. Tyrosine signal transducer and activator of transcription 3 Homo sapiens