Title : Estrogen-related receptor γ is a novel target for Lower-Chlorinated Polychlorinated Biphenyls and their hydroxylated and sulfated metabolites.

Pub. Date : 2019 Nov

PMID : 31491697






1 Functional Relationships(s)
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1 All of the tested chemicals could bind to ERRgamma with the Kd (dissociation constant) values ranging from not available (NA) to 3.2 muM 4"-OH-PCB 12 showed the highest binding affinity with Kd value of 3.2 muM, which was comparable to that of a synthetic ERRgamma agonist GSK4716. GSK 4716 estrogen related receptor gamma Homo sapiens