Pub. Date : 2019
PMID : 31482070
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Inhibition of Glyoxalase-I Leads to Reduced Proliferation, Migration and Colony Formation, and Enhanced Susceptibility to Sorafenib in Hepatocellular Carcinoma. | Sorafenib | glyoxalase I | Homo sapiens |
| 2 | The aim of this study was to analyze Glo-I in hepatocellular carcinoma (HCC) and the effect of the multi-tyrosine kinase inhibitor sorafenib on Glo-I. | Sorafenib | glyoxalase I | Homo sapiens |
| 3 | Sorafenib treatment revealed elevation of Glo-I (10 muM: 209 +- 25%) and MGO. | Sorafenib | glyoxalase I | Homo sapiens |
| 4 | In turn, sorafenib increases Glo-I. | Sorafenib | glyoxalase I | Homo sapiens |
| 5 | Co-treatment using Glo-I inhibitors could enhance susceptibility of HCC to sorafenib. | Sorafenib | glyoxalase I | Homo sapiens |